LC-MS based proteomics for the elucidation of molecular processes involved in CoV2-host-interactions

Prof. Dr. Andreas Tholey
Prof. Dr. Andreas Tholey

Proteomics & Bioanalytics, Institute for Experimental Medicine, Kiel University, 24150 Kiel, Germany

Hospitals involved

University Hospital Schleswig-Holstein (UKSH)Halle/Saale, Germany

Type of analysis

We perform diverse types of analyses for the quantitative analysis of host-cell proteomes upon challenge with either (recombinant) proteins of CoV2 or with the full virus. Aside from classical abundance-targeted proteomics we also try to decipher posttranslational modifications involved.

Further activities regarding development of LC-MS based infection testing and the characterization of antibodies are planned but have not been started yet.